GMÜ 490 series butterfly valves
The GEMÜ 490 series butterfly valve is suitable for pharmaceutical manufacturing applications involving freeze-drying processes with critical operating conditions.
Many pharmaceutical manufacturing procedures are based on bio-technological processes. Often, their molecular structure is extremely complex and their liquid form is unstable, which is why many bio-pharmaceuticals cannot be stored directly. Freeze-drying is the gentlest procedure for conserving the active ingredient solution.
To overcome the disadvantages of conventional freeze-drying processes, Meridion developed a technology for freeze-drying pharmaceuticals in bulk, which has several steps:
The GEMÜ 490 butterfly valve plays a key role in the process. It is based on the design of concentric soft seal valves and is lined with PFA or PTFE. After the frozen globules have fallen through the cooling tower and are collected in the freeze-dryer, the butterfly valve closes upwards and the vacuum can be applied.